Vitamin B12 or Cobalamin is a water soluble vitamin which is very essential to the human body. Vitamin B12 is required in the synthesis of red blood cells and DNA. Deficiency of vitamin B12 is known to disrupt several bodily functions and there are various signs that can detect it.

When the level of vitamin B12 is low in the body, the patient gets too tired and is listless all the time, nausea and diarrhea are also commonly seen in these people.

The common symptoms associated with vitamin B12 deficiency are: yellow tinge on the skin, red tongue, mouth ulcers, pins and needles, disoriented walk, disturbed vision, irritability and depression.

It is said that people who are older are more likely to be deficient in vitamin B12 in comparison to others. The requirement of vitamin B12 varies from person to person depending on age and sex.

It is unimaginable to link vitamin deficiency with neurological disorder. However, vitamin B12 deficiency can lead to several neurological side effects. A 2018 research study had found a rare combination of acute exacerbation of psychiatric manifestations, brain atrophy, severe anemia with coronary insufficiency, and premature graying of hair in a 55 year old man deficient in vitamin B12.

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